Grants: Instructions
The Colorado Center for Drug Discovery (C2D2), invites
researchers to submit small molecule drug discovery-related proposals to be
considered for C2D2 support. This
RFP specifically targets investigators that have starting compounds (“hits or
leads”) which require chemical synthesis and/or analog preparation. This
program is an opportunity for collaborative, integrated research in biology and
chemistry on structure-activity relationships (SAR) of novel compounds through
an iterative and parallel optimization process. In particular, investigators that could benefit
from the following types of assistance are encouraged to apply:
- Funding. Up to $40,000 for PI/Co-PI
lab-based biological research activities related to screening compounds against
novel targets of human disease.
- Synthesis and/or medicinal chemistry
support to advance ongoing drug discovery efforts. Includes
preparation of literature compounds, structural confirmation of screening hits,
analog design and synthesis, as well as lead
compound scale up expansion through molecular modeling techniques.
- In
vitro metabolism or in vivo pharmacokinetic (PK)/pharmacological support. Examples of support include metabolism
studies, permeability, and rodent PK studies.
Please note
that projects related to the following topics are beyond the current scope of
the solicitation and will not be considered:
- Target
identification or validation (e.g. knock-in/knock-out studies)
- High-throughput
screening projects
- siRNA-related
projects
- Vaccines
or biologics (peptides, proteins, or monoclonal antibodies)
Key 2015 dates
At the present time, C2D2 is not accepting proposals.
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